Article Gold Open Access 2025

Early detection of cognitive decline with deep learning and graph-based modeling

MethodsX
Journal · Vol. 14 · Art. 103405
Abstract

In today's world, increasing stress and depression significantly impact cognitive well-being, making early detection of cognitive impairment essential for timely intervention. This work introduces a Multimodal Fusion Cognitive Assessment Framework that leverages advanced deep learning and graph intelligence to enhance early identification accuracy. Traditional tools like the Montreal Cognitive Assessment (MOCA) are limited in adaptability, prompting the need for a more dynamic, data-driven approach. The framework is validated using datasets involving cognitive tests, voice samples, and physiological signals. It enables a scalable, personalized, and adaptive cognitive assessment system that improves early detection and supports targeted intervention strategies. By integrating deep learning and information fusion, this approach addresses the complexity of cognitive health in a modern context. • This paper introduces Multimodal Deep Learning Integration, incorporating MOCA scores, behavioral data, speech signals, and physiological parameters using GAT, TAT, and CNN-LSTM models to capture diverse cognitive indicators. • The proposed model achieves superior performance through Information Fusion via Heterogeneous GNNs, effectively merging cross-domain data to enable holistic cognitive state assessment via inter-modality learning. • This paper applies Reinforcement Learning (RL) to personalize user interactions based on real-time cognitive and stress cues, reducing cognitive overload and enhancing engagement. © 2025 The Author(s)

Keywords

Author Keywords

Deep learning Cognitive assessment Graph neural networks Multimodal fusion

Index Keywords

Skill human Article cognitive defect Deep learning cognitive impairment assessment cognitive neuroscience contrastive speech learning convolutional neural network early diagnosis graph attention network graph neural network heterogeneous graph neural network long short term memory network Montreal cognitive assessment Multimodal Cognitive Assessment Framework reinforcement (psychology) reinforcement learning (machine learning) time aware transformer
Author Affiliations
Computer Science and Engineering, Amity University, Noida, UP, India
Funding & Acknowledgements
No funding information
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