Teachers frequently employ STEM-based learning in the classroom. As technology evolves, the educational sector must update its learning materials. Using voxel-based game learning media is one method. This learning medium includes games that incorporate some of the learning contained within it. This study aims to address the questions raised regarding the challenges and opportunities associated with implementing iSTEM with Roblox in education. A Systematic Literature Review (SLR) was conducted following the PRISMA methodology to explore articles indexed in Scopus from 2019 to 2023. The search returned 393 articles, which were then filtered using inclusion and exclusion criteria, such as publication year, level of education, educational class, demography, journal indexer, analytical material, insights, and reasoning abilities. According to the SLR analysis, there are six significant themes revealed including the main principles of iSTEM, iSTEM implementation, iSTEM development and improvement, the use of Roblox, the potential and benefits of Roblox, and the challenges and effects of Roblox games. © 2025 American Institute of Physics Inc.. All rights reserved.
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