The purpose of this study is to investigate the use of e-books, as well as interactive and non-interactive elements, as a way to present learning content, and the effect of application of e-books to nursing education on learning effectiveness and cognitive load of students in Department of Nursing. This study used quasi-experiment research method to conduct an experiment on two classes of different students receiving instruction from the same teacher and using the same teaching materials. The research results showed that e-books had a significant effect on the improvement of learning effectiveness in both classes. Compared with students using non-interactive e-books, the improvement of learning effectiveness of students using interactive e-books was more significant. In terms of cognitive load, cognitive load was gradually decreased during learning process. However, a certain extent of cognitive load still existed. © 2018, Springer Nature Switzerland AG.
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